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Clinical significance of transcranial magnetic stimulation (TMS) in the treatment of pharmacoresistant depression: synthesis of recent data

Mark A Demitrack 1, Michael E Thase Transcranial magnetic stimulation (TMS) is a novel treatment for patients with major depressive disorder. Although clearly safer and better tolerated than many other pharmacotherapeutic options or electroconvulsive therapy, questions have persisted about the magnitude of the efficacy of TMS in patients with pharmacoresistant depression, and the clinical significance of these […]

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Transcranial magnetic stimulation (TMS) for major depression: a multisite, naturalistic, observational study of quality of life outcome measures in clinical practice

Philip G Janicak 1, David L Dunner, Scott T Aaronson, Linda L Carpenter, Terrence A Boyadjis, David G Brock, Ian A Cook, Karl Lanocha, Hugh B Solvason, Dafna Bonneh-Barkay, Mark A Demitrack Abstract Background: Transcranial magnetic stimulation (TMS) is an effective and safe therapy for major depressive disorder (MDD). This study assessed quality of life (QOL) and functional status outcomes for depressed patients after an acute course […]

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Resources and Research

Use of Transcranial Magnetic Stimulation for Depression

Monitoring Editor: Alexander Muacevic and John R Adler Sukaina Rizvi1 and Ali M Khan2 Prefrontal TMS therapy repeated daily for four to six weeks is a neuromodulation technique approved by the US Food and Drug Administration for the treatment of major depressive disorder (MDD) in patients resistant to medications. This technique utilizes electromagnetic induction to excite neuronal […]

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Effects of Pulse Width and Electrode Placement on the Efficacy and Cognitive Effects of Electroconvulsive Therapy

Harold A. Sackeim, Ph.D., Joan Prudic, M.D., Mitchell S. Nobler, M.D., Linda Fitzsimons, R.N., Sarah H. Lisanby, M.D., Nancy Payne, C.S.W., Robert M. Berman, M.D., Ph.D., Eva-Lotta Brakemeier, M.A., Tarique Perera, M.D., and D. P. Devanand, M.D. While electroconvulsive therapy (ECT) in major depression is effective, cognitive effects limit its use. Reducing the width of the electrical pulse and using the right unilateral electrode […]

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Resources and Research

Efficacy of repetitive transcranial magnetic stimulation in treatment-resistant depression: the evidence thus far

Aditya Somani1,* and Sujita Kumar Kar2 National Library of Medicine Depression is a common mental disorder, which attributes to significant morbidity, disability and burden of care. A significant number of patients with depression still remain symptomatic after adequate trials of antidepressant treatment as well as psychotherapy, which is often referred to as treatment-resistant depression. Neuromodulation techniques—like electroconvulsive […]

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Resources and Research

Transcranial magnetic stimulation (TMS): Hope for stubborn depression

October 27, 2020 By Adam P. Stern, MD, Contributor Harvard Health Publishing Depression is the leading cause of disability in the United States among people ages 15 to 44. While there are many effective treatments for depression, first-line approaches such as antidepressants and psychotherapy do not work for everyone. In fact, approximately two-thirds of people with depression don’t […]

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Resources and Research

Is There Evidence for Effectiveness of Transcranial Magnetic Stimulation in the Treatment of Psychiatric Disorders?

Biju Basil, MD, DPM, Jamal Mahmud, MD, DPM, Maju Mathews, MD, MRCPsych, Dip PSYCH,Carlos Rodriguez, MD, and Babatunde Adetunji, MD, DPM Abstract Transcranial magnetic stimulation (TMS), since its introduction in 1985, has been studied for its efficacy in different psychiatric disorders. It has been touted to be an effective treatment modality for major depression, obsessive compulsive disorder, Tourette […]

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