Resources and Research

Efficacy of repetitive transcranial magnetic stimulation in treatment-resistant depression: the evidence thus far

Aditya Somani1,* and Sujita Kumar Kar2

National Library of Medicine

Depression is a common mental disorder, which attributes to significant morbidity, disability and burden of care. A significant number of patients with depression still remain symptomatic after adequate trials of antidepressant treatment as well as psychotherapy, which is often referred to as treatment-resistant depression. Neuromodulation techniques—like electroconvulsive therapy, vagus nerve stimulation, transcranial magnetic stimulation (TMS) and transcranial direct current stimulation, may be useful augmenting techniques in depression, mostly recommended for treatment-resistant cases…

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