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Success story: Rethinking solutions to depression

Tallahassee Democrat I have always had an interest in the world around me, including a fascination with emerging studies and technological advances which are being accomplished.  I’m a huge fan of Nova, History Channel, and nature programs because they reveal amazing information.  Information that, just a few years ago, didn’t exist or wasn’t easily accessible, […]

Effectiveness of theta burst versus high-frequency repetitive transcranial magnetic stimulation in patients with depression (THREE-D): a randomised non-inferiority trial

Daniel M Blumberger 1, Fidel Vila-Rodriguez 2, Kevin E Thorpe 3, Kfir Feffer 4, Yoshihiro Noda 5, Peter Giacobbe 6, Yuliya Knyahnytska 7, Sidney H Kennedy 8, Raymond W Lam 9, Zafiris J Daskalakis 10, Jonathan Downar 11 Background: Treatment-resistant major depressive disorder is common; repetitive transcranial magnetic stimulation (rTMS) by use of high-frequency (10 Hz) left-side dorsolateral prefrontal cortex stimulation is an evidence-based treatment for this disorder. Intermittent theta burst stimulation (iTBS) is a newer form […]

Accelerated intermittent theta burst stimulation treatment in medication-resistant major depression: A fast road to remission?

Romain Duprat 1, Stefanie Desmyter 2, De Raedt Rudi 3, Kees van Heeringen 2, Dirk Van den Abbeele 2, Hannelore Tandt 2, Jasmina Bakic 3, Gilles Pourtois 3, Josefien Dedoncker 1, Myriam Vervaet 2, Sara Van Autreve 2, Gilbert M D Lemmens 2, Chris Baeken 4 Affiliations expand Abstract Although accelerated repetitive Transcranial Magnetic Stimulation (rTMS) paradigms and intermittent Theta-burst Stimulation (iTBS) may have the potency to result in superior clinical outcomes in Treatment Resistant Depression (TRD), accelerated iTBS treatment has […]

Accelerated repetitive transcranial magnetic stimulation in the treatment of depression

Paul B Fitzgerald 1 2, Kate E Hoy 3, David Elliot 3, R N Susan McQueen 3, Lenore E Wambeek 3, Zafiris J Daskalakis 4 Affiliations expand Free PMC article Abstract Repetitive transcranial magnetic stimulation (rTMS) is increasingly used clinically in the treatment of patients with major depressive disorder (MDD). However, rTMS treatment response can be slow. Early research suggests that accelerated forms of rTMS may be effective […]

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Stanford Neuromodulation Therapy (SNT): A Double-Blind Randomized Controlled Trial

Eleanor J Cole 1, Angela L Phillips 1, Brandon S Bentzley 1, Katy H Stimpson 1, Romina Nejad 1, Fahim Barmak 1, Clive Veerapal 1, Naushaba Khan 1, Kirsten Cherian 1, Emily Felber 1, Randi Brown 1, Elizabeth Choi 1, Sinead King 1, Heather Pankow 1, James H Bishop 1, Azeezat Azeez 1, John Coetzee 1, Rachel Rapier 1, Nicole Odenwald 1, David Carreon 1, Jessica Hawkins 1, Maureen Chang 1, Jennifer Keller 1, Kristin Raj 1, Charles DeBattista 1, Booil Jo 1, Flint M Espil 1, Alan F Schatzberg 1, Keith D Sudheimer 1, Nolan R Williams 1 Affiliations expand Abstract Objective: Depression is the leading cause of disability worldwide, and half of patients with […]

Clinical significance of transcranial magnetic stimulation (TMS) in the treatment of pharmacoresistant depression: synthesis of recent data

Mark A Demitrack 1, Michael E Thase Transcranial magnetic stimulation (TMS) is a novel treatment for patients with major depressive disorder. Although clearly safer and better tolerated than many other pharmacotherapeutic options or electroconvulsive therapy, questions have persisted about the magnitude of the efficacy of TMS in patients with pharmacoresistant depression, and the clinical significance of these […]

Efficacy of repetitive transcranial magnetic stimulation in treatment-resistant depression: the evidence thus far

Aditya Somani1,* and Sujita Kumar Kar2 National Library of Medicine Depression is a common mental disorder, which attributes to significant morbidity, disability and burden of care. A significant number of patients with depression still remain symptomatic after adequate trials of antidepressant treatment as well as psychotherapy, which is often referred to as treatment-resistant depression. Neuromodulation techniques—like electroconvulsive […]

Transcranial magnetic stimulation (TMS): Hope for stubborn depression

October 27, 2020 By Adam P. Stern, MD, Contributor Harvard Health Publishing Depression is the leading cause of disability in the United States among people ages 15 to 44. While there are many effective treatments for depression, first-line approaches such as antidepressants and psychotherapy do not work for everyone. In fact, approximately two-thirds of people with depression don’t […]

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Is There Evidence for Effectiveness of Transcranial Magnetic Stimulation in the Treatment of Psychiatric Disorders?

Biju Basil, MD, DPM, Jamal Mahmud, MD, DPM, Maju Mathews, MD, MRCPsych, Dip PSYCH,Carlos Rodriguez, MD, and Babatunde Adetunji, MD, DPM Abstract Transcranial magnetic stimulation (TMS), since its introduction in 1985, has been studied for its efficacy in different psychiatric disorders. It has been touted to be an effective treatment modality for major depression, obsessive compulsive disorder, Tourette […]